Interpreting Effect Sizes and Clinical Relevance of Pharmacological Interventions for Fibromyalgia
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چکیده
منابع مشابه
Interpreting Effect Sizes and Clinical Relevance of Pharmacological Interventions for Fibromyalgia
Duloxetine, milnacipran, and pregabalin are approved by the United States Food and Drug Administration for the management of fibromyalgia. A number of meta-analyses, pooled analyses, and systematic reviews have been published in recent years involving the efficacy of these three medications for pain in fibromyalgia. Despite being based on the same clinical data, some analyses found these treatm...
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OBJECTIVES To synthesise the available evidence on pharmacological and non-pharmacological interventions recommended for fibromyalgia syndrome (FMS). METHODS Electronic databases including MEDLINE, PsycINFO, Scopus, the Cochrane Controlled Trials Registry and the Cochrane Library were searched for randomised controlled trials comparing any therapeutic approach as recommended in FMS guidelines...
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There is no universal guideline or rule of thumb for judging the practical importance or substantive significance of a standardized effect size estimate for an intervention. Instead, one must develop empirical benchmarks of comparison that reflect the nature of the intervention being evaluated, its target population, and the outcomemeasure ormeasures beingused.Thisapproach is applied to the ass...
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متن کاملPharmacological treatment of fibromyalgia.
Fibromyalgia (FM) is a common syndrome characterised by widespread pain and at least 11/18 painful tender points that requires multimodal pharmacological treatment also combined with non-pharmacological therapy. Various drugs currently are available to control the complex and different symptoms reported by patients. Only three drugs (duloxetine, milnacipram, pregabalin) are approved by the Amer...
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ژورنال
عنوان ژورنال: Pain and Therapy
سال: 2013
ISSN: 2193-8237,2193-651X
DOI: 10.1007/s40122-013-0011-1